Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.44 |
| ▸ | WNT3 | P56703 | 2/20 | 0.44 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833419 | 0.93 | RIPK1 (0.47) | RIPK1NR1H2NR1H3WNT3SFRP1 | |
| SCHEMBL30833425 | 0.92 | RIPK1 (0.45) | RIPK1NR1H2NR1H3WNT3SFRP1 | |
| SCHEMBL30833520 | 0.82 | MEN1 (0.44) | NR1H2NR1H3WNT3SFRP1GPR119 | |
| SCHEMBL30833395 | 0.80 | APP (0.46) | RIPK1NR1H2NR1H3WNT3SFRP1 | |
| SCHEMBL17948857 | 0.80 | GPR119 (0.52) | SFRP1GPR119MEN1KMT2ASTS | |
| SCHEMBL29530166 | 0.80 | GPR119 (0.52) | SFRP1GPR119MEN1KMT2ASTS | |
| SCHEMBL30833494 | 0.80 | NR1H2 (0.45) | RIPK1NR1H2NR1H3GPR119MEN1 | |
| SCHEMBL28384353 | 0.79 | NR1H2 (0.41) | NR1H2NR1H3GPR119STSHTR2A | |
| SCHEMBL30833481 | 0.79 | NR1H3 (0.48) | RIPK1NR1H2NR1H3WNT3SFRP1 | |
| SCHEMBL30833514 | 0.77 | GPR119 (0.44) | WNT3SFRP1GPR119MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |