Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | WNT3 | P56703 | 2/20 | 0.36 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833381 | 0.92 | MEN1 (0.46) | MEN1KMT2AGPR119PIK3CDTRPV1 | |
| SCHEMBL30833473 | 0.83 | GPR119 (0.42) | MEN1KMT2AGPR119PIK3CDTRPV1 | |
| SCHEMBL30833412 | 0.83 | GPR119 (0.42) | MEN1KMT2AGPR119PIK3CDTRPV1 | |
| SCHEMBL17949423 | 0.82 | GPR119 (0.54) | GPR119PIK3CDMMP13 | |
| SCHEMBL17948853 | 0.74 | GPR119 (0.53) | GPR119PIK3CDMMP13 | |
| SCHEMBL17948854 | 0.74 | GPR119 (0.53) | GPR119PIK3CDMMP13 | |
| SCHEMBL17942528 | 0.73 | GPR119 (0.55) | GPR119MMP13 | |
| SCHEMBL30833502 | 0.73 | MEN1 (0.42) | MEN1KMT2ATRPV1WNT3SFRP1 | |
| SCHEMBL30833482 | 0.72 | MEN1 (0.40) | MEN1KMT2AWNT3SFRP1NR1H2 | |
| SCHEMBL30833454 | 0.72 | KMT2A (0.40) | MEN1KMT2AGPR119TRPV1WNT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |