Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833410 | 0.89 | GPR119 (0.45) | GPR119MEN1KMT2ATRPV1ALOX5AP | |
| SCHEMBL30833434 | 0.85 | MEN1 (0.42) | GPR119MEN1KMT2ATRPV1ALOX5AP | |
| SCHEMBL30833444 | 0.83 | MEN1 (0.45) | GPR119MEN1KMT2ATRPV1PIK3CD | |
| SCHEMBL17948853 | 0.82 | GPR119 (0.53) | GPR119PIK3CDMMP13 | |
| SCHEMBL30833412 | 0.82 | GPR119 (0.42) | GPR119MEN1KMT2ATRPV1PIK3CD | |
| SCHEMBL30833390 | 0.79 | OPRD1 (0.44) | MEN1KMT2ATRPV1APPHTR1A | |
| SCHEMBL1763578 | 0.76 | LMNA (0.47) | GPR119MEN1KMT2AAPPHTR1A | |
| SCHEMBL1763583 | 0.76 | LMNA (0.47) | GPR119MEN1KMT2AAPPHTR1A | |
| SCHEMBL30833395 | 0.76 | APP (0.46) | GPR119MEN1KMT2AAPPHTR1A | |
| SCHEMBL30833391 | 0.76 | PDE8B (0.39) | MEN1KMT2ATRPV1ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |