Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833515 | 0.92 | ALDH1A1 (0.36) | ALDH1A1KMT2AHPGDMEN1HTT | |
| SCHEMBL17942475 | 0.84 | FAAH (0.39) | ALDH1A1KMT2AHPGDMEN1HTT | |
| SCHEMBL30833478 | 0.82 | ALDH1A1 (0.36) | ALDH1A1KMT2AHPGDMEN1HTT | |
| SCHEMBL17942486 | 0.79 | L3MBTL1 (0.37) | ALDH1A1KMT2AHPGDMEN1HTT | |
| SCHEMBL18025956 | 0.73 | ALDH1A1 (0.38) | ALDH1A1KMT2AHPGDMEN1HTT | |
| SCHEMBL17942530 | 0.71 | PIK3C3 (0.39) | ALDH1A1KMT2AHTTSMN1; SMN2CNR2 | |
| SCHEMBL17949145 | 0.71 | L3MBTL1 (0.36) | ALDH1A1KMT2AHPGDMEN1HTT | |
| SCHEMBL25573724 | 0.69 | FAAH (0.37) | HPGDSMN1; SMN2CNR2FAAHLMNA | |
| SCHEMBL18025946 | 0.69 | CNR2 (0.37) | ALDH1A1KMT2AHPGDMEN1CNR2 | |
| SCHEMBL17942439 | 0.68 | PIK3C3 (0.37) | ALDH1A1KMT2AHPGDMEN1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |