Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833515 | 0.90 | ALDH1A1 (0.36) | ALDH1A1KMT2AMEN1HPGDPIK3C3 | |
| SCHEMBL17942439 | 0.83 | PIK3C3 (0.37) | ALDH1A1KMT2AMEN1HPGDPIK3C3 | |
| SCHEMBL30833458 | 0.82 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1HPGDHTT | |
| SCHEMBL17942530 | 0.80 | PIK3C3 (0.39) | ALDH1A1KMT2APIK3C3HTTRORC | |
| SCHEMBL30833382 | 0.77 | SFRP1 (0.38) | KMT2AMEN1RORC | |
| SCHEMBL18025946 | 0.74 | CNR2 (0.37) | ALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL17942486 | 0.73 | L3MBTL1 (0.37) | ALDH1A1KMT2AMEN1HPGDPIK3C3 | |
| Danicamtiv SCHEMBL17942408 | 0.72 | L3MBTL1 (0.36) | ALDH1A1KMT2AMEN1HPGDHTT | |
| Danicamtiv SCHEMBL17942536 | 0.72 | L3MBTL1 (0.36) | ALDH1A1KMT2AMEN1HPGDHTT | |
| Danicamtiv SCHEMBL17942407 | 0.72 | L3MBTL1 (0.36) | ALDH1A1KMT2AMEN1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |