Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 6/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17942348 | 1.00 | CA12 (0.37) | CA12CA1CA2CA9FAAH | |
| SCHEMBL17942345 | 0.91 | CA12 (0.38) | CA12CA1CA2CA9FAAH | |
| SCHEMBL19996432 | 0.87 | CA12 (0.40) | CA12CA1CA2CA9NAMPT | |
| SCHEMBL17949180 | 0.87 | TRPV1 (0.44) | CA12CA1CA2CA9EPHX2 | |
| SCHEMBL30833432 | 0.85 | EPHX2 (0.37) | EPHX2RORCPRKAA2FPR2FPR1 | |
| SCHEMBL17949197 | 0.83 | TRPV1 (0.46) | CA12CA1CA2CA9FAAH | |
| SCHEMBL17942555 | 0.83 | GPR119 (0.40) | GPR119 | |
| SCHEMBL17949193 | 0.83 | ALPL (0.37) | CA12CA1CA2CA9FAAH | |
| SCHEMBL18011677 | 0.83 | ALPL (0.37) | CA12CA1CA2CA9FAAH | |
| SCHEMBL17949196 | 0.83 | ALPL (0.37) | CA12CA1CA2CA9FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |