Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 3/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | WNT3 | P56703 | 1/20 | 0.33 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.33 |
| ▸ | LHCGR | P22888 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833430 | 0.91 | LMNA (0.39) | EPHX2RORCLMNAMEN1KMT2A | |
| SCHEMBL17942348 | 0.85 | CA12 (0.37) | EPHX2RORCFPR2FPR1PRKAA2 | |
| SCHEMBL30833479 | 0.85 | CA12 (0.37) | EPHX2RORCFPR2FPR1PRKAA2 | |
| SCHEMBL30833412 | 0.81 | GPR119 (0.42) | MEN1KMT2AWNT3SFRP1PIK3CD | |
| Trifluoroacetic Acid SCHEMBL30833404 | 0.77 | RORC (0.40) | EPHX2RORCLMNAMEN1KMT2A | |
| SCHEMBL30833456 | 0.77 | RORC (0.35) | EPHX2RORCLMNAWNT3SFRP1 | |
| SCHEMBL17942345 | 0.75 | CA12 (0.38) | EPHX2RORCFPR2FPR1LMNA | |
| SCHEMBL30833427 | 0.75 | RORC (0.36) | EPHX2RORCLMNAWNT3SFRP1 | |
| SCHEMBL30833471 | 0.74 | RORC (0.36) | EPHX2RORCLMNAKMT2AWNT3 | |
| SCHEMBL30833383 | 0.73 | MEN1 (0.42) | EPHX2RORCLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |