Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3672142 | 0.90 | KDM4E (0.44) | LMNAALOX5BACE1HTTKDM4E | |
| SCHEMBL27671451 | 0.87 | LMNA (0.40) | LMNAALOX5BACE1HTTKDM4E | |
| SCHEMBL27865228 | 0.87 | LMNA (0.40) | LMNAALOX5BACE1HTTKDM4E | |
| SCHEMBL14430757 | 0.84 | LMNA (0.44) | LMNAALOX5BACE1HTTKDM4E | |
| SCHEMBL5598385 | 0.84 | LMNA (0.44) | LMNAALOX5BACE1HTTKDM4E | |
| SCHEMBL27852474 | 0.83 | AKT1 (0.46) | LMNAALOX5BACE1HTTKDM4E | |
| SCHEMBL27848174 | 0.83 | LMNA (0.37) | LMNAALOX5BACE1HTTKDM4E | |
| SCHEMBL9331500 | 0.82 | HSD17B10 (0.47) | LMNABACE1HTTKDM4EHSD17B10 | |
| SCHEMBL27865232 | 0.82 | LMNA (0.36) | LMNAALOX5BACE1HTTKDM4E | |
| SCHEMBL22498754 | 0.82 | MGAM (0.38) | LMNAHTTKDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110330422-A | A kind of preparation method of 2,6- diethyl -4- methylphenyl acetic acid | 江苏中旗科技股份有限公司 | 2019-10-15 | — | — | CN | claimed |
| CN-109096106-A | A kind of preparation method of pinoxaden key intermediate | 南京齐正化学有限公司 | 2018-12-28 | — | — | CN | claimed |
| CN-113121341-A | Method for synthesizing 2, 6-diethyl-4-methyl phenylacetate | 江苏中旗科技股份有限公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-110526927-A | A kind of preparation method of pinoxaden | JIANGSU FLAG CHEM IND CO LTD | 2019-12-03 | — | — | CN | disclosed |
| CN-110330422-A | A kind of preparation method of 2,6- diethyl -4- methylphenyl acetic acid | 江苏中旗科技股份有限公司 | 2019-10-15 | — | — | CN | disclosed |
| CN-110330422-A | A kind of preparation method of 2,6- diethyl -4- methylphenyl acetic acid | 江苏中旗科技股份有限公司 | 2019-10-15 | — | — | CN | disclosed |
| CN-109096106-A | A kind of preparation method of pinoxaden key intermediate | 南京齐正化学有限公司 | 2018-12-28 | — | — | CN | disclosed |
| US-8383853-B2 | Method for preparing 2,6-diethyl-4-methylphenylacetic acid | BAYER CROPSCIENCE AG (DE) | 2013-02-26 | — | — | US | disclosed |
| CN-102014630-A | Herbicidal composition comprising a pyridazinone compound with a specific herbicide and a specific safener | SUMITOMO CHEMICAL CO | 2011-04-13 | — | — | CN | disclosed |
| US-20100261934-A1 | Method for Preparing 2,6-Diethyl-4-Methylphenylacetic Acid | BAYER CROPSCIENCE AG (DE) | 2010-10-14 | — | — | US | disclosed |
| CN-101693657-A | 2, 6-diethyl-4-methylphenyl substituted tetramic acid derivatives | BAYER CROPSCIENCE AG | 2010-04-14 | — | — | CN | disclosed |
| US-20080318776-A1 | 2,6-Diethyl-4-Methylphenyl-Substituted Tetramic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2008-12-25 | — | — | US | disclosed |
| CN-101094855-A | 2, 6-diethyl-4-methylphenyl substituted tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2007-12-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261934-A1 | Method for Preparing 2,6-Diethyl-4-Methylphenylacetic Acid | DDT, TET1, DDC | LMNA 4009/4885ALOX5 1501/4885BACE1 4489/4885 |
| US-20080318776-A1 | 2,6-Diethyl-4-Methylphenyl-Substituted Tetramic Acid Derivatives | DDT, TET1, TET3 | LMNA 4223/4885ALOX5 1282/4885BACE1 4236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.