Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | RHOA | P61586 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190644 | 1.00 | MEN1 (0.41) | MEN1KMT2AKCNH2HRH4SIRT6 | |
| SCHEMBL30833799 | 0.89 | SIRT6 (0.50) | MEN1KMT2AHRH4SIRT6HRH3 | |
| SCHEMBL4784574 | 0.89 | SIRT6 (0.50) | MEN1KMT2AHRH4SIRT6HRH3 | |
| SCHEMBL29190586 | 0.87 | MAPK1 (0.43) | MEN1KMT2AHRH3RHOAMAPK1 | |
| SCHEMBL30833680 | 0.87 | MAPK1 (0.43) | MEN1KMT2AHRH3RHOAMAPK1 | |
| SCHEMBL30833677 | 0.87 | MAPK1 (0.43) | MEN1KMT2AHRH3RHOAMAPK1 | |
| SCHEMBL29190522 | 0.81 | KCNH2 (0.44) | KCNH2MAPK1 | |
| SCHEMBL30833743 | 0.81 | KCNH2 (0.44) | KCNH2MAPK1 | |
| SCHEMBL29190649 | 0.80 | HRH4 (0.44) | MEN1KMT2AKCNH2HRH4SIRT6 | |
| SCHEMBL30833658 | 0.80 | HRH4 (0.44) | MEN1KMT2AKCNH2HRH4SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |