SCHEMBL30833685

SCHEMBL30833685

O=[N+]([O-])c1ccc2c(N3CCOCC3)n[nH]c2c1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 4/20 0.52
ALDH1A1 P00352 4/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2C9 P11712 2/20 0.48
HPGD P15428 1/20 0.48
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
TDP1 Q9NUW8 3/20 0.46
POLB P06746 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
ACHE P22303 1/20 0.45
MAPT P10636 4/20 0.44
AKR1C3 P42330 1/20 0.43
LMNA P02545 2/20 0.43
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
BLM P54132 1/20 0.42
THRB P10828 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29190669 1.00 MAPK1 (0.52) MAPK1ALDH1A1CYP1A2CYP2C9HPGD
SCHEMBL2466571 0.90 MAPK1 (0.52) MAPK1ALDH1A1CYP1A2CYP2C9HPGD
SCHEMBL30833680 0.89 MAPK1 (0.43) MAPK1ALDH1A1CYP1A2CYP2C9HPGD
SCHEMBL30833677 0.89 MAPK1 (0.43) MAPK1ALDH1A1CYP1A2CYP2C9HPGD
SCHEMBL29190586 0.89 MAPK1 (0.43) MAPK1ALDH1A1CYP1A2CYP2C9HPGD
SCHEMBL30833799 0.85 SIRT6 (0.50) MAPK1ALDH1A1CYP1A2CYP2C9HPGD
SCHEMBL4784574 0.85 SIRT6 (0.50) MAPK1ALDH1A1CYP1A2CYP2C9HPGD
SCHEMBL2927346 0.79 CTSB (0.53) ALDH1A1CYP2C9MEN1KMT2APOLB
SCHEMBL27228014 0.78 KDM4E (0.53) ALDH1A1HPGDKMT2ATDP1SMN1; SMN2
SCHEMBL30860970 0.78 KDM4E (0.53) ALDH1A1HPGDKMT2ATDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113896744-B Selective EGFR inhibitor 成都先导药物开发股份有限公司 2024-04-16 CN disclosed