Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784574 | 1.00 | SIRT6 (0.50) | SIRT6HRH4HRH3LMNAAPP | |
| SCHEMBL4781802 | 0.90 | MAPT (0.50) | SIRT6HRH4HRH3LMNAAPP | |
| SCHEMBL29190644 | 0.89 | MEN1 (0.41) | SIRT6HRH4HRH3LMNAAPP | |
| SCHEMBL30833752 | 0.89 | MEN1 (0.41) | SIRT6HRH4HRH3LMNAAPP | |
| SCHEMBL4785656 | 0.85 | LMNA (0.54) | SIRT6HRH4HRH3LMNAAPP | |
| SCHEMBL29190669 | 0.85 | MAPK1 (0.52) | LMNAACHEALDH1A1MAPK1GAA | |
| SCHEMBL30833685 | 0.85 | MAPK1 (0.52) | LMNAACHEALDH1A1MAPK1GAA | |
| SCHEMBL30833670 | 0.80 | HTT (0.54) | LMNAALDH1A1GAAHTTCYP3A4 | |
| SCHEMBL29190572 | 0.78 | MAPK1 (0.43) | LMNAMAPK1CYP1A2CYP3A4MAPT | |
| SCHEMBL30833644 | 0.78 | MAPK1 (0.43) | LMNAMAPK1CYP1A2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |