Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 7/20 | 0.44 |
| ▸ | AXL | P30530 | 3/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 3/20 | 0.32 |
| ▸ | BCR | P11274 | 3/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190564 | 1.00 | MAPK1 (0.44) | MAPK1AXLFGFR1FGFR2PDPK1 | |
| SCHEMBL30833676 | 0.81 | AXL (0.45) | MAPK1AXLFGFR1FGFR2PDPK1 | |
| SCHEMBL29190572 | 0.78 | MAPK1 (0.43) | MAPK1GSK3B | |
| SCHEMBL30833644 | 0.78 | MAPK1 (0.43) | MAPK1GSK3B | |
| SCHEMBL29190556 | 0.74 | MAPK1 (0.54) | MAPK1AXLPDPK1JAK2 | |
| SCHEMBL30833725 | 0.74 | AXL (0.50) | MAPK1AXLJAK2 | |
| SCHEMBL4785556 | 0.74 | AXL (0.50) | MAPK1AXLJAK2 | |
| SCHEMBL31144185 | 0.74 | MAPK1 (0.50) | MAPK1 | |
| SCHEMBL30833762 | 0.69 | MAPK1 (0.44) | MAPK1AXLFGFR1PDPK1JAK2 | |
| SCHEMBL30833743 | 0.69 | KCNH2 (0.44) | MAPK1AXLFGFR1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |