Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 16/20 | 0.47 |
| ▸ | ULK1 | O75385 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 3/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | CCNK | O75909 | 1/20 | 0.43 |
| ▸ | CCND3 | P30281 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833764 | 0.90 | IGF1R (0.45) | ALKULK1METCDK2FLT3 | |
| SCHEMBL30833702 | 0.88 | PTK2 (0.46) | ULK1CDK2CDK9PTK2 | |
| SCHEMBL30833696 | 0.86 | ALK (0.52) | ALKULK1METFLT3PTK2 | |
| SCHEMBL30833661 | 0.85 | ALK (0.46) | ALKULK1CCNA2CDK2FLT3 | |
| SCHEMBL30833776 | 0.85 | ALK (0.48) | ALKMETFLT3PTK2 | |
| SCHEMBL29190632 | 0.84 | ALK (0.63) | ALKULK1METFLT3PTK2 | |
| SCHEMBL30833724 | 0.84 | ALK (0.52) | ALKULK1METCDK2FLT3 | |
| SCHEMBL30833666 | 0.83 | ALK (0.49) | ALKMETFLT3 | |
| SCHEMBL30833718 | 0.81 | JAK3 (0.47) | ALKMETCDK2FLT3PTK2 | |
| SCHEMBL30833714 | 0.78 | ALK (0.46) | ALKULK1METCDK2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |