Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 17/20 | 0.52 |
| ▸ | FLT3 | P36888 | 2/20 | 0.45 |
| ▸ | MET | P08581 | 2/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | ULK1 | O75385 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833718 | 0.91 | JAK3 (0.47) | ALKFLT3METMAPK9PTK2 | |
| SCHEMBL30833666 | 0.89 | ALK (0.49) | ALKFLT3MET | |
| SCHEMBL30833757 | 0.86 | ALK (0.47) | ALKFLT3METULK1PTK2 | |
| SCHEMBL30833672 | 0.85 | ALK (0.51) | ALKMAPK9MAPK10ULK1PTK2 | |
| SCHEMBL30833776 | 0.84 | ALK (0.48) | ALKFLT3METPTK2 | |
| SCHEMBL30833785 | 0.84 | ALK (0.51) | ALKFLT3MAPK9MAPK10ULK1 | |
| SCHEMBL30833724 | 0.84 | ALK (0.52) | ALKFLT3METMAPK9MAPK10 | |
| SCHEMBL29190551 | 0.83 | ALK (0.67) | ALKFLT3METPTK2 | |
| SCHEMBL30833625 | 0.79 | ALK (0.52) | ALKFLT3ULK1 | |
| SCHEMBL29190707 | 0.79 | ALK (0.52) | ALKFLT3ULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |