Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 17/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833696 | 0.89 | ALK (0.52) | ALKFLT3MET | |
| SCHEMBL30833656 | 0.85 | ALK (0.48) | ALKIGF1RFLT3 | |
| SCHEMBL29190714 | 0.85 | ALK (0.61) | ALKFLT3EGFRMET | |
| SCHEMBL30833672 | 0.83 | ALK (0.51) | ALKIGF1REGFR | |
| SCHEMBL30833757 | 0.83 | ALK (0.47) | ALKFLT3MET | |
| SCHEMBL30833776 | 0.81 | ALK (0.48) | ALKFLT3MET | |
| SCHEMBL30833718 | 0.81 | JAK3 (0.47) | ALKIGF1RFLT3EGFRMET | |
| SCHEMBL30833724 | 0.81 | ALK (0.52) | ALKIGF1RFLT3EGFRMET | |
| SCHEMBL29190530 | 0.80 | ALK (0.61) | ALKFLT3EGFRMET | |
| SCHEMBL30833643 | 0.73 | ALK (0.43) | ALKMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |