Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 13/20 | 0.46 |
| ▸ | ULK1 | O75385 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.44 |
| ▸ | CDK2 | P24941 | 4/20 | 0.44 |
| ▸ | CCNK | O75909 | 3/20 | 0.43 |
| ▸ | CDK9 | P50750 | 3/20 | 0.43 |
| ▸ | CCND3 | P30281 | 2/20 | 0.43 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833634 | 0.90 | IGF1R (0.46) | IGF1R | |
| SCHEMBL29190628 | 0.90 | IGF1R (0.46) | IGF1R | |
| SCHEMBL30833808 | 0.88 | PTK2 (0.47) | ULK1CDK2CDK9IGF1R | |
| SCHEMBL30833785 | 0.86 | ALK (0.51) | ALKULK1FLT3IGF1R | |
| SCHEMBL30833687 | 0.85 | ALK (0.50) | ALKULK1FLT3 | |
| SCHEMBL30833757 | 0.85 | ALK (0.47) | ALKULK1CCNA2CDK2CCNK | |
| SCHEMBL30833669 | 0.85 | ALK (0.46) | ALKULK1CCNA2CDK2CCNK | |
| SCHEMBL30833700 | 0.84 | KDR (0.52) | ALKULK1CDK2CDK9FLT3 | |
| SCHEMBL30833656 | 0.83 | ALK (0.48) | ALKFLT3IGF1RAXL | |
| SCHEMBL29190632 | 0.82 | ALK (0.63) | ALKULK1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |