Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 10/20 | 0.47 |
| ▸ | ULK1 | O75385 | 4/20 | 0.45 |
| ▸ | CDK1 | P06493 | 3/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 5/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | CDK7 | P50613 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833661 | 0.88 | ALK (0.46) | ULK1CDK2IGF1RCDK9 | |
| SCHEMBL30833634 | 0.88 | IGF1R (0.46) | IGF1R | |
| SCHEMBL29190628 | 0.88 | IGF1R (0.46) | IGF1R | |
| SCHEMBL30833702 | 0.85 | PTK2 (0.46) | PTK2ULK1CDK1CDK4CDK2 | |
| SCHEMBL29190594 | 0.83 | PTK2 (0.52) | PTK2ULK1CDK1CDK4CDK2 | |
| SCHEMBL30833633 | 0.81 | EGFR (0.47) | PTK2ULK1CDK1CDK4CDK2 | |
| SCHEMBL30833740 | 0.80 | PTK2 (0.50) | PTK2ULK1CDK1CDK4CDK2 | |
| SCHEMBL30833797 | 0.76 | ALK (0.44) | PTK2IGF1R | |
| SCHEMBL30833785 | 0.74 | ALK (0.51) | ULK1IGF1R | |
| SCHEMBL30833638 | 0.73 | PTK2 (0.45) | PTK2ULK1CDK1CDK4CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |