Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 12/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 4/20 | 0.39 |
| ▸ | JAK1 | P23458 | 3/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833785 | 0.91 | ALK (0.51) | ALKIGF1RAURKAFLT3EGFR | |
| SCHEMBL30833718 | 0.85 | JAK3 (0.47) | ALKIGF1RAURKAPKMYT1JAK3 | |
| SCHEMBL30833687 | 0.84 | ALK (0.50) | ALKFLT3EGFR | |
| SCHEMBL29190642 | 0.82 | ALK (0.59) | ALKPKMYT1JAK3JAK1FLT3 | |
| SCHEMBL30833661 | 0.81 | ALK (0.46) | ALKIGF1RFLT3 | |
| SCHEMBL30833656 | 0.81 | ALK (0.48) | ALKIGF1RFLT3 | |
| SCHEMBL30833669 | 0.80 | ALK (0.46) | ALKFLT3 | |
| SCHEMBL30833634 | 0.78 | IGF1R (0.46) | IGF1R | |
| SCHEMBL29190628 | 0.78 | IGF1R (0.46) | IGF1R | |
| SCHEMBL30833754 | 0.75 | MAPT (0.36) | IGF1RAURKAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |