Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 14/20 | 0.51 |
| ▸ | FLT3 | P36888 | 2/20 | 0.43 |
| ▸ | ULK1 | O75385 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833687 | 0.92 | ALK (0.50) | ALKFLT3ULK1EGFRMAPK9 | |
| SCHEMBL30833797 | 0.91 | ALK (0.44) | ALKFLT3EGFRAURKAIGF1R | |
| SCHEMBL30833656 | 0.89 | ALK (0.48) | ALKFLT3IGF1R | |
| SCHEMBL30833661 | 0.86 | ALK (0.46) | ALKFLT3ULK1IGF1R | |
| SCHEMBL30833699 | 0.85 | EGFR (0.49) | ALKULK1EGFRAURKAIGF1R | |
| SCHEMBL30833669 | 0.84 | ALK (0.46) | ALKFLT3ULK1 | |
| SCHEMBL30833696 | 0.84 | ALK (0.52) | ALKFLT3ULK1MAPK9MAPK10 | |
| SCHEMBL30833700 | 0.84 | KDR (0.52) | ALKFLT3ULK1EGFRAURKA | |
| SCHEMBL29190551 | 0.81 | ALK (0.67) | ALKFLT3EGFR | |
| SCHEMBL30833625 | 0.79 | ALK (0.52) | ALKFLT3ULK1AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |