SCHEMBL30834905

SCHEMBL30834905

COc1cc(O)c2c(c1C(=O)/C=C/c1ccc(O)cc1)OC(C)(C)C(O)C2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NFKB1 P19838 5/20 0.53
▸ NFKB2 Q00653 5/20 0.53
▸ RELA Q04206 5/20 0.53
▸ DPP4 P27487 1/20 0.53
▸ PDPK1 O15530 1/20 0.50
▸ TTR P02766 1/20 0.50
▸ ALOX5 P09917 1/20 0.50
▸ ESR1 P03372 1/20 0.48
▸ ABCG2 Q9UNQ0 3/20 0.47
▸ TDP1 Q9NUW8 3/20 0.47
▸ MAPT P10636 5/20 0.46
▸ CYP3A4 P08684 4/20 0.46
▸ CYP2D6 P10635 1/20 0.46
▸ CYP2C9 P11712 1/20 0.46
▸ CYP2C19 P33261 1/20 0.46
▸ KMT2A Q03164 4/20 0.45
▸ MEN1 O00255 3/20 0.45
▸ KCNA3 P22001 1/20 0.45
▸ NPSR1 Q6W5P4 1/20 0.45
▸ CAPN1 P07384 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xanthohumol B SCHEMBL29934961 0.85 NFKB1 (0.56) NFKB1NFKB2RELADPP4PDPK1
Xanthohumol B SCHEMBL12961703 0.85 NFKB1 (0.56) NFKB1NFKB2RELADPP4PDPK1
SCHEMBL25256060 0.84 MAPT (0.53) NFKB1NFKB2RELAABCG2MAPT
SCHEMBL5997891 0.82 MAOB (0.52) NFKB1NFKB2RELAABCG2TDP1
SCHEMBL14523845 0.82 MAOB (0.52) NFKB1NFKB2RELAABCG2TDP1
SCHEMBL14523859 0.79 PTPN1 (0.47) NFKB1NFKB2RELAESR1ABCG2
SCHEMBL15704340 0.74 NFKB1 (0.54) NFKB1NFKB2RELADPP4PDPK1
SCHEMBL30834930 0.72 PDPK1 (0.65) NFKB1NFKB2RELADPP4PDPK1
SCHEMBL14249291 0.72 NFKB1 (0.78) NFKB1NFKB2RELADPP4PDPK1
SCHEMBL14249292 0.72 NFKB1 (0.78) NFKB1NFKB2RELADPP4PDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2026-04-30 — — US disclosed
EP-4593631-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME Mars, Incorporated (US) 2025-08-06 — — EP disclosed
CN-119968127-A Animal food compositions with improved palatability and customizable properties and methods of making the same 玛氏公司 2025-05-09 — — CN disclosed
WO-2024073025-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-04 — — WO disclosed
EP-4344552-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-03 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME PIGS, TAS2R13, CEL NFKB1 1806/4885NFKB2 1989/4885RELA 3882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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