Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.38 |
| ▸ | GPR183 | P32249 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31556485 | 0.91 | MAPT (0.48) | MAPTTACR1GPR119GPR183JAK2 | |
| Trifluoroacetic Acid SCHEMBL30835923 | 0.87 | P2RY14 (0.39) | TACR1GPR183P2RY14MMP13 | |
| SCHEMBL30836018 | 0.85 | MAPT (0.44) | MAPTTACR1GPR119GPR183JAK2 | |
| Trifluoroacetic Acid SCHEMBL30835994 | 0.81 | P2RY14 (0.35) | TACR1GPR183P2RY14MMP13 | |
| SCHEMBL30835859 | 0.81 | MAPT (0.51) | MAPTTACR1GPR119GPR183JAK2 | |
| SCHEMBL30835990 | 0.80 | MAPT (0.50) | MAPTTACR1GPR119GPR183JAK2 | |
| SCHEMBL28654152 | 0.80 | GPR119 (0.45) | TACR1GPR119GPR183STS | |
| SCHEMBL30835992 | 0.78 | MAPT (0.50) | MAPTTACR1GPR119GPR183JAK2 | |
| SCHEMBL30836034 | 0.77 | MAPT (0.47) | MAPTTACR1GPR119GPR183JAK2 | |
| SCHEMBL30836009 | 0.76 | MAPT (0.46) | MAPTTACR1GPR119GPR183JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587424-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | Bridgene Biosciences, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059317-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | BRIDGENE BIOSCIENCES, INC. (US) | 2024-03-21 | — | — | WO | disclosed |