Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31556508 | 0.94 | TACR1 (0.44) | GPR119STSALDH2TGFBR1MAPT | |
| SCHEMBL30835966 | 0.94 | TACR1 (0.44) | GPR119STSALDH2TGFBR1MAPT | |
| SCHEMBL31556549 | 0.88 | USP30 (0.43) | GPR119STSMAPTPOLBGRM5 | |
| SCHEMBL30836036 | 0.88 | USP30 (0.43) | GPR119STSMAPTPOLBGRM5 | |
| SCHEMBL30836020 | 0.86 | GPR119 (0.52) | GPR119STSALDH2TGFBR1MAPT | |
| SCHEMBL1198456 | 0.84 | GPR119 (0.61) | GPR119STS | |
| SCHEMBL30835993 | 0.80 | GPR119 (0.48) | GPR119STSALDH2TGFBR1MAPT | |
| SCHEMBL27400109 | 0.80 | TEAD1 (0.53) | POLB | |
| SCHEMBL30836039 | 0.80 | TEAD1 (0.53) | POLB | |
| SCHEMBL24493567 | 0.77 | GPR119 (0.61) | GPR119ALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587424-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | Bridgene Biosciences, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059317-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | BRIDGENE BIOSCIENCES, INC. (US) | 2024-03-21 | — | — | WO | disclosed |