Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30835966 | 1.00 | TACR1 (0.44) | TACR1GPR119STSTGFBR1GRM5 | |
| SCHEMBL30836036 | 0.94 | USP30 (0.43) | TACR1GPR119STSGRM5USP30 | |
| SCHEMBL31556549 | 0.94 | USP30 (0.43) | TACR1GPR119STSGRM5USP30 | |
| SCHEMBL30835997 | 0.94 | GPR119 (0.47) | GPR119STSTGFBR1GRM5POLB | |
| SCHEMBL30835993 | 0.87 | GPR119 (0.48) | TACR1GPR119STSTGFBR1USP30 | |
| SCHEMBL31556577 | 0.81 | TEAD1 (0.56) | POLB | |
| SCHEMBL27399837 | 0.81 | TEAD1 (0.56) | POLB | |
| SCHEMBL30835946 | 0.81 | TEAD1 (0.56) | POLB | |
| SCHEMBL27399893 | 0.81 | TEAD1 (0.56) | POLB | |
| SCHEMBL30836020 | 0.80 | GPR119 (0.52) | GPR119STSTGFBR1MAPTALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119894866-A | YAP/TAZ-TEAD oncoprotein inhibitors | 布里奇恩生物科学公司 | 2025-04-25 | — | — | CN | disclosed |