Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31556571 | 0.83 | RORC (0.43) | GRM5STSRORCTACR1MAPT | |
| SCHEMBL3788239 | 0.78 | MAP3K12 (0.47) | SYKSTSRORCTACR1MAPT | |
| SCHEMBL30835950 | 0.77 | RORC (0.39) | STSRORCTACR1MAPTGPR119 | |
| SCHEMBL24111414 | 0.76 | GPR119 (0.46) | GRM5RORCGPR119 | |
| SCHEMBL30324512 | 0.76 | GPR119 (0.46) | GRM5RORCGPR119 | |
| SCHEMBL30272618 | 0.75 | AR (0.40) | RORCTACR1GPR119ALDH2 | |
| SCHEMBL22462783 | 0.75 | AR (0.40) | RORCTACR1GPR119ALDH2 | |
| SCHEMBL17793695 | 0.75 | HRH3 (0.46) | SYKSTSRORCTACR1MAPT | |
| SCHEMBL30835991 | 0.73 | RORC (0.41) | STSRORCTACR1MAPTGPR119 | |
| SCHEMBL29913023 | 0.73 | JAK3 (0.41) | SYKSTSRORCTACR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587424-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | Bridgene Biosciences, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| CN-119894866-A | YAP/TAZ-TEAD oncoprotein inhibitors | 布里奇恩生物科学公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024059317-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | BRIDGENE BIOSCIENCES, INC. (US) | 2024-03-21 | — | — | WO | disclosed |