Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30835941 | 0.89 | EPHX2 (0.36) | EPHX2MCL1ALDH2STSRORC | |
| SCHEMBL30835991 | 0.89 | RORC (0.41) | MCL1ALDH2STSRORCTGFBR1 | |
| SCHEMBL20512225 | 0.84 | CYP1A2 (0.34) | EPHX2MAPT | |
| SCHEMBL30835950 | 0.76 | RORC (0.39) | ALDH2STSRORCTACR1MAPT | |
| SCHEMBL31556571 | 0.69 | RORC (0.43) | STSRORCTACR1MAPT | |
| SCHEMBL28658591 | 0.69 | CYP1A2 (0.40) | EPHX2MCL1MAPT | |
| SCHEMBL30835998 | 0.69 | SYK (0.43) | ALDH2STSRORCTACR1MAPT | |
| SCHEMBL30835993 | 0.68 | GPR119 (0.48) | ALDH2STSRORCTGFBR1TACR1 | |
| SCHEMBL28711089 | 0.68 | EPHX2 (0.40) | EPHX2STSRORC | |
| SCHEMBL22462783 | 0.67 | AR (0.40) | EPHX2ALDH2RORCTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587424-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | Bridgene Biosciences, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| CN-119894866-A | YAP/TAZ-TEAD oncoprotein inhibitors | 布里奇恩生物科学公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024059317-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | BRIDGENE BIOSCIENCES, INC. (US) | 2024-03-21 | — | — | WO | disclosed |