Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 15/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20602052 | 0.75 | FAAH (0.61) | FAAHCHRNA4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3759949 | 0.74 | FAAH (0.56) | FAAHCHRNA4CHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL3749168 | 0.73 | FAAH (0.55) | FAAHCHRNA4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3335026 | 0.72 | CHRNA4 (0.48) | FAAHCHRNA4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3337016 | 0.71 | CHRNA4 (0.44) | FAAHCHRNA4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5174301 | 0.70 | ELANE (0.43) | ELANE | |
| SCHEMBL3333856 | 0.70 | CHRNA4 (0.62) | FAAHCHRNA4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3189682 | 0.70 | ELANE (0.43) | ELANE | |
| SCHEMBL11234361 | 0.70 | CHRNB2 (0.51) | ELANECHRNA4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL13475920 | 0.69 | ALDH1A1 (0.43) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117769443-A | Fibroblast activation protein inhibitor and use thereof | 3B制药有限公司 | 2024-03-26 | — | — | CN | disclosed |