Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27965294 | 0.73 | KDM4E (0.44) | ELANEALDH1A1KDM4EGAA | |
| SCHEMBL5174301 | 0.71 | ELANE (0.43) | ELANERIPK1SCN4AHTR2CHTR2B | |
| SCHEMBL7067465 | 0.70 | ALDH1A1 (0.43) | ELANERIPK1SCN4AALDH1A1KDM4E | |
| Quinoxaline SCHEMBL14719935 | 0.70 | ELANE (0.51) | ELANERIPK1SCN4AKDM4EHTR2C | |
| SCHEMBL13475920 | 0.70 | ALDH1A1 (0.43) | ELANERIPK1SCN4AALDH1A1KDM4E | |
| SCHEMBL30838459 | 0.70 | ELANE (0.48) | ELANE | |
| Quinoxaline SCHEMBL14719936 | 0.70 | ELANE (0.51) | ELANERIPK1SCN4AKDM4EHTR2C | |
| SCHEMBL30705003 | 0.70 | ELANE (0.48) | ELANERIPK1SCN4AALDH1A1GAA | |
| SCHEMBL69939 | 0.70 | KDM4E (0.54) | ALDH1A1KDM4EASPHKDM8 | |
| SCHEMBL168919 | 0.69 | ELANE (0.54) | ELANERIPK1SCN4AKDM4EHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230130980-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | TECHFIELDS PHARMA CO., LTD. (CN) | 2023-04-27 | — | — | US | disclosed |
| US-11485744-B2 | High penetration prodrug compositions of antimicrobials and antimicrobial-related compounds | TECHFIELDS PHARMA CO., LTD. (CN) | 2022-11-01 | — | — | US | disclosed |
| US-20210206782-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | TECHFIELDS PHARMA CO., LTD. (CN) | 2021-07-08 | — | — | US | disclosed |
| US-10233197-B2 | High penetration prodrug compositions of antimicrobials and antimicrobial-related compounds | TECHFIELDS PHARMA CO., LTD. (CN) | 2019-03-19 | — | — | US | disclosed |
| US-20180222921-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | PREMIER RESEARCH INTERNATIONAL, LLC | 2018-08-09 | — | — | US | disclosed |
| US-9969751-B2 | High penetration prodrug compositions of antimicrobials and antimicrobial-related compounds | TECHFIELDS PHARMA CO., LTD. (CN) | 2018-05-15 | — | — | US | disclosed |
| US-20130018029-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | TECHFIELDS PHARMA CO., LTD (CN) | 2013-01-17 | — | — | US | disclosed |
| US-20120157371-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | PREMIER RESEARCH INTERNATIONAL, LLC | 2012-06-21 | — | — | US | disclosed |
| US-20100040548-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | TECHFIELDS PHARMA CO., LTD (CN) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180222921-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | SLC7A1, VIP, HPGDS | ELANE 556/4885RIPK1 4209/4885SCN4A 4325/4885 |
| US-20210206782-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | SLC7A1, VIP, HAMP | ELANE 458/4885RIPK1 4021/4885SCN4A 4226/4885 |
| US-11485744-B2 | High penetration prodrug compositions of antimicrobials and antimicrobial-related compounds | SLC7A1, VIP, HPGDS | ELANE 556/4885RIPK1 4209/4885SCN4A 4325/4885 |
| US-20230130980-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | SLC7A1, VIP, HPGDS | ELANE 556/4885RIPK1 4209/4885SCN4A 4325/4885 |
| US-20130018029-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | SLC7A1, VIP, HAMP | ELANE 458/4885RIPK1 4021/4885SCN4A 4226/4885 |
| US-10233197-B2 | High penetration prodrug compositions of antimicrobials and antimicrobial-related compounds | SLC7A1, VIP, HAMP | ELANE 458/4885RIPK1 4021/4885SCN4A 4226/4885 |
| US-20100040548-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | SLC7A1, VIP, HAMP | ELANE 458/4885RIPK1 4021/4885SCN4A 4226/4885 |
| US-20120157371-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | SLC7A1, VIP, HPGDS | ELANE 556/4885RIPK1 4209/4885SCN4A 4325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.