Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5674929 | 0.80 | EPHX1 (0.53) | AKR1C3AKR1C2CA12CA1CA2 | |
| SCHEMBL2653483 | 0.80 | EPHX1 (0.53) | AKR1C3AKR1C2CA12CA1CA2 | |
| SCHEMBL27536782 | 0.80 | AKR1C3 (0.53) | AKR1C3AKR1C2LMNATSHRMEN1 | |
| SCHEMBL5739656 | 0.78 | MAPT (0.51) | CXCR2CXCR1CYP3A4ALDH1A1GAA | |
| SCHEMBL13723847 | 0.78 | AKR1C3 (0.70) | AKR1C3AKR1C2CXCR2CXCR1LMNA | |
| SCHEMBL28202578 | 0.78 | AKR1C3 (0.56) | AKR1C3AKR1C2LMNATSHRMEN1 | |
| SCHEMBL28569065 | 0.78 | CA12 (0.53) | CA12CA1CA2CA4CA9 | |
| SCHEMBL2655181 | 0.77 | AKR1C3 (0.47) | AKR1C3AKR1C2CA12CA1CA2 | |
| SCHEMBL5739780 | 0.77 | ALDH1A1 (0.57) | CXCR2CXCR1KDM4EALDH1A1GAA | |
| SCHEMBL6266741 | 0.76 | CTSD (0.64) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024071629-A1 | NOVEL FLUORENE DERIVATIVE COMPOUND AND USE THEREOF | (주)제이디바이오사이언스 | 2024-04-04 | — | — | WO | disclosed |