Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.53 |
| ▸ | CA1 | P00915 | 5/20 | 0.53 |
| ▸ | CA2 | P00918 | 5/20 | 0.53 |
| ▸ | CA9 | Q16790 | 5/20 | 0.53 |
| ▸ | CA4 | P22748 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17365594 | 0.84 | POLB (0.66) | KMT2AMEN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7748974 | 0.84 | POLB (0.66) | KMT2AMEN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL16307627 | 0.80 | MAPT (0.63) | CA12CA1CA2CA9CA4 | |
| SCHEMBL6625967 | 0.78 | KMT2A (0.72) | KMT2AMEN1LMNAMAPTPOLB | |
| SCHEMBL30838569 | 0.78 | AKR1C3 (0.46) | CA12CA1CA2CA9CA4 | |
| SCHEMBL9913187 | 0.77 | PTGS2 (0.72) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL13723847 | 0.77 | AKR1C3 (0.70) | LMNAPTGS2TSHR | |
| SCHEMBL4372856 | 0.76 | MAPT (0.76) | CA12CA1CA2CA9CA4 | |
| SCHEMBL27291251 | 0.76 | MAPT (0.76) | CA12CA1CA2CA9CA4 | |
| SCHEMBL3151838 | 0.76 | MAPT (0.76) | CA12CA1CA2CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112851557-B | Sulfo-substituted biaryl compound or salt thereof, and preparation method and application thereof | 上海辉启生物医药科技有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-112851557-A | Sulfo-substituted biaryl compound or salt thereof, and preparation method and application thereof | 上海辉启生物医药科技有限公司 | 2021-05-28 | — | — | CN | disclosed |