Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7246016 | 0.87 | TDP1 (0.64) | TDP1L3MBTL1HTR2BALDH1A1MAPT | |
| SCHEMBL9977361 | 0.84 | MAOA (0.47) | TDP1L3MBTL1HTR2BALDH1A1MAPT | |
| SCHEMBL11404428 | 0.82 | ALDH1A1 (0.69) | TDP1L3MBTL1HTR2BALDH1A1MAPT | |
| SCHEMBL3142640 | 0.81 | MAPT (0.72) | TDP1L3MBTL1ALDH1A1MAPTRAB9A | |
| SCHEMBL29395306 | 0.80 | MAOB (0.60) | TDP1L3MBTL1HTR2BALDH1A1MAPT | |
| SCHEMBL29799860 | 0.80 | MAOB (0.60) | TDP1L3MBTL1HTR2BALDH1A1MAPT | |
| SCHEMBL132696 | 0.80 | MAOB (0.60) | TDP1L3MBTL1HTR2BALDH1A1MAPT | |
| SCHEMBL30838849 | 0.79 | RAB9A (0.45) | ALDH1A1MAPTRAB9AAPPMAOA | |
| SCHEMBL11253494 | 0.79 | LMNA (0.56) | TDP1HTR2BALDH1A1MAPTRAB9A | |
| Methane SCHEMBL29238124 | 0.78 | MAOB (0.58) | TDP1L3MBTL1HTR2BALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736199-A | 6H-dibenzo [ b, d ] pyran derivative substituted by 3-position oxygen-containing group, and preparation method and application thereof | 西安交通大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-117736200-A | 2- [ (6H-dibenzo [ b, d ] pyran-3-yl) oxy ] amide derivative and preparation method and application thereof | 西安交通大学 | 2024-03-22 | — | — | CN | disclosed |