SCHEMBL30839233

SCHEMBL30839233

Brc1ccc2c(c1)Oc1ccccc1N2

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 7/20 0.65
AHR P35869 3/20 0.59
HTR2B P41595 2/20 0.47
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
GAA P10253 2/20 0.43
MAPT P10636 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
LMNA P02545 1/20 0.43
ALPL P05186 1/20 0.43
HSP90AA1 P07900 1/20 0.43
ALPI P09923 1/20 0.43
ALPG P10696 1/20 0.43
TLR9 Q9NR96 1/20 0.43
HTR7 P34969 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
DHODH Q02127 1/20 0.39
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13833013 1.00 ALOX5 (0.65) ALOX5AHRHTR2BMEN1KMT2A
Benzene SCHEMBL28149598 0.90 AHR (0.54) ALOX5AHRHTR2BMEN1KMT2A
SCHEMBL1985922 0.90 AHR (0.58) ALOX5AHRHTR2BMAPTLMNA
SCHEMBL29689592 0.90 AHR (0.58) ALOX5AHRHTR2BMAPTLMNA
SCHEMBL31168827 0.89 ALOX5 (0.65) ALOX5AHRHTR2BMEN1KMT2A
SCHEMBL11536877 0.89 ALOX5 (0.65) ALOX5AHRHTR2BMEN1KMT2A
SCHEMBL46736 0.86 AHR (0.56) ALOX5AHRHTR2BMEN1KMT2A
Phenoxazine SCHEMBL6310178 0.81 ALOX5 (1.00) ALOX5HTR2BMEN1KMT2AGAA
Phenoxazine SCHEMBL28844098 0.81 ALOX5 (1.00) ALOX5HTR2BMEN1KMT2AGAA
Phenoxazine SCHEMBL29355714 0.81 ALOX5 (1.00) ALOX5HTR2BMEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117820345-A Blue light material based on dibenzofuran-aza condensed ring, preparation and application thereof 山西大同大学 2024-04-05 CN disclosed