SCHEMBL1985922

SCHEMBL1985922

Brc1ccc2c(c1)Oc1cc(Br)ccc1N2

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 6/20 0.58
ALOX5 P09917 2/20 0.46
TGM2 P21980 1/20 0.41
CES1 P23141 1/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
BLM P54132 1/20 0.38
PDPK1 O15530 1/20 0.36
JAK2 O60674 1/20 0.36
SNCA P37840 1/20 0.36
CMA1 P23946 1/20 0.35
BRD4 O60885 1/20 0.35
HTR2C P28335 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29689592 1.00 AHR (0.58) AHRALOX5TGM2CES1CA12
Benzene SCHEMBL28149598 0.96 AHR (0.54) AHRALOX5TGM2CES1CA12
SCHEMBL46736 0.92 AHR (0.56) AHRALOX5TGM2CES1CA12
SCHEMBL30839233 0.90 ALOX5 (0.65) AHRALOX5LMNAMAPTHTR2B
SCHEMBL13833013 0.90 ALOX5 (0.65) AHRALOX5LMNAMAPTHTR2B
SCHEMBL13082340 0.88 AHR (0.47) AHRALOX5TGM2CES1CA12
SCHEMBL28731967 0.84 AHR (0.47) AHRALOX5
SCHEMBL10171010 0.80 TGM2 (0.54) AHRTGM2CES1CA12CA1
SCHEMBL30869575 0.80 AHR (0.42) AHRALOX5TGM2CES1CA12
SCHEMBL30869584 0.80 AHR (0.42) AHRALOX5TGM2CES1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
US-20250393469-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO LTD (KR) 2025-12-25 US disclosed
US-12433150-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2025-09-30 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
CN-118652426-A Water-blocking and oxygen-blocking polyimide material containing phenoxazine structure and amide bond, and preparation method and application thereof 扬州科实包装新材料有限公司 2024-09-17 CN disclosed
WO-2024071042-A1 COMPOUND, HOLE TRANSPORT MATERIAL, AND PHOTOELECTRIC CONVERSION ELEMENT USING SAID COMPOUND 保土谷化学工業株式会社 2024-04-04 WO disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed
US-11678573-B2 Organic compound, organic light-emitting diode and organic light-emitting device containing the compound LG DISPLAY CO., LTD. (KR) 2023-06-13 US disclosed
US-11678573-B2 Organic compound, organic light-emitting diode and organic light-emitting device containing the compound LG DISPLAY CO., LTD. (KR) 2023-06-13 US disclosed
CN-111018837-B Organic compound, OLED having the same, and organic light emitting device 乐金显示有限公司 2023-04-28 CN disclosed
US-20110130306-A1 PRO-FLUORESCENT PROBES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-06-02 US disclosed
US-7842823-B2 Fluorogenic probes for reactive oxygen species THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-11-30 US disclosed
US-20100133992-A1 COMPOUND COMPRISING PHOSPHORESCENCE UNIT, EMITTING POLYMER AND ORGANIC EMITTING DEVICE COMPRISING THE EMITTING POLYMER SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-06-03 US disclosed
US-20100133992-A1 COMPOUND COMPRISING PHOSPHORESCENCE UNIT, EMITTING POLYMER AND ORGANIC EMITTING DEVICE COMPRISING THE EMITTING POLYMER SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-06-03 US disclosed
WO-2009152102-A2 PRO-FLUORESCENT PROBES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-12-17 WO disclosed
EP-1948824-A2 FLUOROGENIC PROBES FOR REACTIVE OXYGEN SPECIES The Regents of the University of California Office of Technology Transfer (US) 2008-07-30 EP disclosed
US-20070141658-A1 Fluorogenic probes for reactive oxygen species THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-06-21 US disclosed
WO-2007050810-A2 FLUOROGENIC PROBES FOR REACTIVE OXYGEN SPECIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-05-03 WO disclosed
US-5756356-A COLORIMETRIC TOYO INK MANUFACTURING CO., LTD. (JP) 1998-05-26 US disclosed
EP-0735368-A1 Method of indicating time or temperature-time accumulated value as color change, and materials therefor TOYO INK MANUFACTURING CO., LTD. (JP) 1996-10-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11678573-B2 Organic compound, organic light-emitting diode and organic light-emitting device containing the compound TYR, NLRP3, OCIAD1 AHR 455/4885ALOX5 1668/4885TGM2 2007/4885
US-12433150-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device ODC1, LEF1, L1CAM AHR 3567/4885ALOX5 2185/4885TGM2 1285/4885
US-20100133992-A1 COMPOUND COMPRISING PHOSPHORESCENCE UNIT, EMITTING POLYMER AND ORGANIC EMITTING DEVICE COMPRISING THE EMITTING POLYMER PUF60, OCIAD1, OCIAD2 AHR 4751/4885ALOX5 1206/4885TGM2 2846/4885
US-20250393469-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SOD1, LIFR, LEF1 AHR 2358/4885ALOX5 3409/4885TGM2 3442/4885
US-20070141658-A1 Fluorogenic probes for reactive oxygen species PRDX1, GPX1, GPX4 AHR 1219/4885ALOX5 905/4885TGM2 3448/4885
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 AHR 4553/4885ALOX5 4658/4885TGM2 3716/4885
US-20110130306-A1 PRO-FLUORESCENT PROBES PRDX5, FIS1, PRDX3 AHR 879/4885ALOX5 2500/4885TGM2 2871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.