SCHEMBL30839892

SCHEMBL30839892

CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 16/20 0.45
▸ APLNR P35414 1/20 0.44
▸ KEAP1 Q14145 1/20 0.43
▸ VIPR1 P32241 1/20 0.42
▸ C5AR1 P21730 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30839888 0.93 APLNR (0.46) GLP1RAPLNRKEAP1C5AR1
SCHEMBL30293824 0.91 GLP1R (0.40) GLP1RKEAP1VIPR1
SCHEMBL30369010 0.88 GLP1R (0.45) GLP1RVIPR1
SCHEMBL29649781 0.88 AGTR2 (0.51) GLP1RVIPR1C5AR1
SCHEMBL30811634 0.87 GLP1R (0.45) GLP1RKEAP1VIPR1C5AR1
SCHEMBL31060878 0.86 ENPEP (0.47) —
SCHEMBL29701259 0.85 GLP1R (0.49) GLP1RVIPR1
SCHEMBL30823264 0.85 APLNR (0.50) GLP1RAPLNRKEAP1C5AR1
SCHEMBL31414089 0.85 APLNR (0.44) GLP1RAPLNRC5AR1
SCHEMBL30455424 0.85 GLP1R (0.50) GLP1RKEAP1VIPR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250082716-A1 REPRESSED ANG 1-7 IN COVID-19 IS INVERSELY ASSOCIATED WITH INFLAMMATION AND COAGULATION UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2025-03-13 — — US claimed
US-20250082716-A1 REPRESSED ANG 1-7 IN COVID-19 IS INVERSELY ASSOCIATED WITH INFLAMMATION AND COAGULATION UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2025-03-13 — — US disclosed
WO-2024054198-A1 REPRESSED ANG 1-7 IN COVID-19 IS INVERSELY ASSOCIATED WITH INFLAMMATION AND COAGULATION UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2024-03-14 — — WO disclosed
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