Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1833210 | 0.89 | GAA (0.67) | LMNAMAPTJAK2GAADRD2 | |
| SCHEMBL30408898 | 0.89 | GAA (0.67) | LMNAMAPTJAK2GAADRD2 | |
| SCHEMBL1835201 | 0.86 | HTR1A (0.56) | LMNAMAPTJAK2GAADRD2 | |
| SCHEMBL17912813 | 0.82 | CYP11B1 (0.56) | LMNAMAPTJAK2GAADRD2 | |
| SCHEMBL10696284 | 0.82 | ALDH1A1 (0.53) | LMNAL3MBTL1CNR1CNR2NPC1 | |
| SCHEMBL6356278 | 0.81 | MAPT (0.60) | LMNAMAPTGAADRD2HTR1A | |
| SCHEMBL9804792 | 0.80 | CYSLTR2 (0.50) | MAPTIDO1FFAR1 | |
| SCHEMBL1837432 | 0.79 | LMNA (0.64) | LMNAMAPTJAK2GAADRD2 | |
| SCHEMBL15079848 | 0.78 | GAA (0.62) | LMNAMAPTJAK2GAADRD2 | |
| SCHEMBL1837148 | 0.78 | JAK2 (0.62) | LMNAMAPTJAK2GAADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1967521-B1 | METHOD FOR PRODUCING POLYMERIZABLE PHOSPHATE ESTER | KAO CORP (JP) | 2013-03-13 | — | — | EP | disclosed |
| US-8207367-B2 | Method for producing polymerizable phosphate ester | KAO CORPORATION (JP) | 2012-06-26 | — | — | US | disclosed |
| CN-101346389-B | Method for producing polymerizable phosphate ester | KAO CORP | 2011-07-06 | — | — | CN | disclosed |
| US-20100227994-A1 | METHOD FOR PRODUCING POLYMERIZABLE PHOSPHATE ESTER | KAO CORPORATION (JP) | 2010-09-09 | — | — | US | disclosed |
| CN-101346389-A | Method for producing polymerizable phosphate ester | KAO CORP (JP) | 2009-01-14 | — | — | CN | disclosed |
| EP-1967521-A1 | METHOD FOR PRODUCING POLYMERIZABLE PHOSPHATE ESTER | Kao Corporation (JP) | 2008-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100227994-A1 | METHOD FOR PRODUCING POLYMERIZABLE PHOSPHATE ESTER | CA4, PHYKPL, INPPL1 | LMNA 1179/4885MAPT 4252/4885JAK2 3321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.