Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | HPN | P05981 | 1/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1626149 | 1.00 | MAPT (0.61) | MAPTALDH1A1ALOX15HSD17B10TDP1 | |
| SCHEMBL29359219 | 0.88 | ALDH1A1 (0.52) | MAPTALDH1A1ALOX15HSD17B10TDP1 | |
| SCHEMBL16245359 | 0.88 | ALDH1A1 (0.52) | MAPTALDH1A1ALOX15HSD17B10TDP1 | |
| SCHEMBL29549838 | 0.84 | MAPT (0.75) | MAPTALDH1A1ALOX15HSD17B10TDP1 | |
| SCHEMBL1204733 | 0.84 | MAPT (0.75) | MAPTALDH1A1ALOX15HSD17B10TDP1 | |
| SCHEMBL12023167 | 0.84 | ALDH1A1 (0.74) | MAPTALDH1A1ALOX15HSD17B10TDP1 | |
| Fluorene SCHEMBL28466769 | 0.81 | MAOA (0.54) | MAPTALDH1A1ALOX15HSD17B10TDP1 | |
| SCHEMBL31727528 | 0.80 | MEN1 (0.53) | MAPTALDH1A1ALOX15HSD17B10TDP1 | |
| SCHEMBL7535295 | 0.79 | MAOA (0.48) | MAPTALDH1A1ALOX15HSD17B10TDP1 | |
| SCHEMBL20918664 | 0.79 | DRD3 (0.44) | MAPTALDH1A1ALOX15HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313210-B | Photochromic indeno-fused naphthopyran compounds with reduced temperature dependence | 光学转变有限公司 | 2024-03-15 | — | — | CN | disclosed |