SCHEMBL7535295

SCHEMBL7535295

Oc1cccc2c1-c1ccccc1CCC2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.48
MAOB P27338 2/20 0.48
BCL2L1 Q07817 1/20 0.48
BAD Q92934 1/20 0.48
CYP2A6 P11509 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.44
HPGD P15428 2/20 0.44
TSHR P16473 3/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPT P10636 2/20 0.42
ALOX15 P16050 2/20 0.42
HSD17B10 Q99714 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
MEN1 O00255 1/20 0.42
USP2 O75604 1/20 0.42
HPN P05981 1/20 0.42
CYP3A4 P08684 1/20 0.42
ALOX5 P09917 1/20 0.42
THRB P10828 1/20 0.42
PTGS1 P23219 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL269511 0.96 BCL2L1 (0.53) MAOAMAOBBCL2L1BADCYP2A6
SCHEMBL19018589 0.81 BCL2L1 (0.64) MAOAMAOBBCL2L1BADL3MBTL1
SCHEMBL30844848 0.79 MAPT (0.61) MAOAMAOBL3MBTL1HPGDTSHR
SCHEMBL1626149 0.79 MAPT (0.61) MAOAMAOBL3MBTL1HPGDTSHR
SCHEMBL23264525 0.76 CYP2A6 (0.48) MAOAMAOBCYP2A6L3MBTL1HPGD
SCHEMBL2564157 0.76 MAPT (0.52) MAOAMAOBBCL2L1BADCYP2A6
SCHEMBL29115116 0.76 MAOA (0.48) MAOAMAOBCYP2A6L3MBTL1HPGD
SCHEMBL24081334 0.76 BCL2L1 (0.38) MAOAMAOBBCL2L1BADL3MBTL1
SCHEMBL12023190 0.75 ALDH1A1 (0.54) MAOAMAOBBCL2L1BADL3MBTL1
SCHEMBL30505637 0.75 CYP2A6 (0.68) MAOAMAOBCYP2A6L3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111909196-B IVB-group-containing bimetallic complex catalyst, and preparation method and application thereof 万华化学集团股份有限公司 2023-05-26 CN claimed
CN-117263897-A Chiral dibenzosubenol compound and asymmetric synthesis method thereof 四川师范大学 2023-12-22 CN disclosed
CN-117263897-A Chiral dibenzosubenol compound and asymmetric synthesis method thereof 四川师范大学 2023-12-22 CN disclosed
CN-114315883-B Dibenzofuran phenol IVB metal complex and preparation method thereof, catalyst system and olefin polymerization method 万华化学集团股份有限公司 2023-10-20 CN disclosed
CN-111909196-B IVB-group-containing bimetallic complex catalyst, and preparation method and application thereof 万华化学集团股份有限公司 2023-05-26 CN disclosed
WO-2002030897-A2 COMPOSITIONS AND METHODS FOR REGULATING THE NERVOUS SYSTEM FILLION GILLES (FR) 2002-04-18 WO disclosed