Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | POLQ | O75417 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21530467 | 1.00 | ABL1 (0.40) | ABL1GRIN2BMDM2KMT2ANPC1 | |
| SCHEMBL27334085 | 0.80 | HSP90AB1 (0.37) | RAB9ASMN1; SMN2POLQMAPTL3MBTL1 | |
| SCHEMBL30770791 | 0.80 | HSP90AB1 (0.37) | RAB9ASMN1; SMN2POLQMAPTL3MBTL1 | |
| SCHEMBL31599692 | 0.72 | P2RX7 (0.44) | RAB9ASMN1; SMN2POLQMAPTL3MBTL1 | |
| SCHEMBL20675726 | 0.71 | KDM4E (0.37) | ABL1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL21306488 | 0.71 | SMN1; SMN2 (0.42) | NPC1RAB9ASMN1; SMN2POLQTDP1 | |
| SCHEMBL30845500 | 0.71 | SMN1; SMN2 (0.42) | NPC1RAB9ASMN1; SMN2POLQTDP1 | |
| SCHEMBL18068216 | 0.71 | GABRP (0.47) | KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30964013 | 0.71 | GABRP (0.47) | KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25433576 | 0.71 | L3MBTL1 (0.41) | ABL1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112312905-B | Tetrazole-containing inhibitors of apoptosis signal-regulating kinase 1 and methods of use thereof | 英安塔制药有限公司 | 2024-03-15 | — | — | CN | disclosed |