Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30845562 | 0.89 | PDK2 (0.38) | PDK2PDK4ALDH1A1HSD17B10HPGD | |
| SCHEMBL8579296 | 0.80 | PDK2 (0.39) | PDK2PDK4ALDH1A1HSD17B10HPGD | |
| SCHEMBL31413076 | 0.77 | PDK2 (0.48) | PDK2PDK4ALDH1A1HSD17B10HPGD | |
| SCHEMBL8583685 | 0.75 | ALDH1A1 (0.42) | PDK2PDK4ALDH1A1HSD17B10HPGD | |
| SCHEMBL8581200 | 0.75 | ALOX5AP (0.37) | PDK2PDK4ALDH1A1HSD17B10HPGD | |
| SCHEMBL24928885 | 0.74 | PTGER4 (0.43) | PDK2PDK4ALDH1A1HSD17B10HPGD | |
| SCHEMBL10986337 | 0.74 | CA1 (0.51) | ALDH1A1HSD17B10TSHRSLC6A3SLC6A4 | |
| SCHEMBL7034611 | 0.74 | CA1 (0.45) | ALDH1A1HSD17B10HPGDTSHRSLC6A3 | |
| SCHEMBL8580134 | 0.74 | YAP1 (0.39) | ALDH1A1HSD17B10HPGDTSHRSMN1; SMN2 | |
| SCHEMBL24928665 | 0.73 | ALDH1A1 (0.42) | ALDH1A1HSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881657-A | Phenyl-sulfamoyl-benzoic acid derivatives as ERAP1 modulators | 格雷沃尔夫治疗有限公司 | 2024-04-12 | — | — | CN | disclosed |