Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 11/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | BRD2 | P25440 | 3/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21033158 | 0.89 | BRD4 (0.50) | USP30BRD4FTOEGLN1BRD2 | |
| SCHEMBL21033470 | 0.84 | KDM4E (0.53) | USP30BRD4FTOBRD2CREBBP | |
| SCHEMBL30845754 | 0.79 | TGFBR1 (0.48) | TGFBR1EGLN1 | |
| SCHEMBL20031288 | 0.75 | USP30 (0.52) | USP30BRD4BRD2 | |
| SCHEMBL8065354 | 0.75 | TGFBR1 (0.50) | TGFBR1EGLN1 | |
| SCHEMBL30845768 | 0.74 | TGFBR1 (0.54) | TGFBR1EGLN1 | |
| SCHEMBL30845780 | 0.73 | TGFBR1 (0.49) | TGFBR1EGLN1 | |
| SCHEMBL30845769 | 0.73 | TGFBR1 (0.46) | TGFBR1EGLN1 | |
| SCHEMBL30845779 | 0.73 | TGFBR1 (0.58) | TGFBR1EGLN1 | |
| SCHEMBL30845778 | 0.73 | EGLN1 (0.64) | TGFBR1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111542523-B | Heterocyclic compounds as PRMT5 inhibitors | 朱比连特埃皮斯科瑞有限责任公司 | 2024-03-29 | — | — | CN | claimed |
| CN-111542523-B | Heterocyclic compounds as PRMT5 inhibitors | 朱比连特埃皮斯科瑞有限责任公司 | 2024-03-29 | — | — | CN | disclosed |