Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | RBP4 | P02753 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21033315 | 0.85 | PTGS1 (0.41) | RBP4KDM4ERAB9ACSNK1DCSNK1E | |
| SCHEMBL30845789 | 0.81 | TGFBR1 (0.43) | RBP4KDM4ECSNK1DCSNK1EALDH1A1 | |
| SCHEMBL26395116 | 0.78 | DRD2 (0.41) | DRD2DRD3KDM4ERAB9AALDH1A1 | |
| SCHEMBL2514311 | 0.78 | PIK3CG (0.39) | KDM4ERAB9APIK3CGNPC1RXFP1 | |
| SCHEMBL21033482 | 0.77 | KDM4E (0.61) | KDM4ERAB9AALDH1A1NPC1RXFP1 | |
| SCHEMBL30845761 | 0.73 | MCHR1 (0.48) | KDM4ERAB9AALDH1A1NPC1 | |
| SCHEMBL14903857 | 0.72 | JUN (0.41) | KDM4ERAB9AALDH1A1NOTUMP2RX7 | |
| SCHEMBL17232815 | 0.72 | DYRK1A (0.49) | RBP4KDM4ERAB9AALDH1A1NPC1 | |
| SCHEMBL2364683 | 0.72 | PIK3CA (0.43) | CSNK1DCSNK1E | |
| SCHEMBL30845788 | 0.72 | GLS (0.37) | DRD2DRD3KDM4ERAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111542523-B | Heterocyclic compounds as PRMT5 inhibitors | 朱比连特埃皮斯科瑞有限责任公司 | 2024-03-29 | — | — | CN | disclosed |