Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.47 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30846578 | 0.99 | SMARCA2 (0.48) | SMARCA2SMARCA4SORT1ACKR3PSEN1 | |
| SCHEMBL30846683 | 0.85 | IDO1 (0.43) | IDO1TSHRALDH1A1NPSR1MAPK1 | |
| SCHEMBL30846618 | 0.82 | IDO1 (0.46) | SORT1IDO1ALDH1A1NPSR1CYP2C9 | |
| SCHEMBL16252564 | 0.78 | SMARCA2 (0.58) | SMARCA2SMARCA4SORT1PSEN1PSEN2 | |
| SCHEMBL20866546 | 0.77 | HTR1E (0.62) | TSHRALDH1A1CYP3A4KDM4ESMN1; SMN2 | |
| SCHEMBL30846693 | 0.75 | NPC1 (0.58) | TSHRALDH1A1CYP3A4KDM4ESMN1; SMN2 | |
| SCHEMBL30846735 | 0.75 | RAB9A (0.59) | SMARCA2SMARCA4TSHRCYP3A4SMN1; SMN2 | |
| SCHEMBL22986541 | 0.74 | IDO1 (0.51) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL20838627 | 0.74 | IDO1 (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL30846657 | 0.73 | PRMT3 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116910-A1 | Heterocycles as WIP1 Inhibitors | PMV PHARMACEUTICALS, INC. | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116910-A1 | Heterocycles as WIP1 Inhibitors | WAPL, WHR1, G3BP1 | SMARCA2 316/4885SMARCA4 165/4885SORT1 3106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.