Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTR1E | P28566 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 2/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30846658 | 0.84 | IDO1 (0.47) | IDO1NPC1RAB9AMEN1LMNA | |
| SCHEMBL30846693 | 0.80 | NPC1 (0.58) | ALDH1A1SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL30846657 | 0.76 | PRMT3 (0.56) | — | |
| SCHEMBL30846587 | 0.76 | KMT2A (0.56) | ALDH1A1SMN1; SMN2IDO1NPC1RAB9A | |
| SCHEMBL30846618 | 0.75 | IDO1 (0.46) | ALDH1A1SMN1; SMN2IDO1AAK1CYP2C9 | |
| SCHEMBL30846683 | 0.70 | IDO1 (0.43) | ALDH1A1SMN1; SMN2IDO1MEN1LMNA | |
| SCHEMBL30846578 | 0.70 | SMARCA2 (0.48) | ALDH1A1IDO1MEN1KMT2ACYP2C9 | |
| SCHEMBL30846697 | 0.69 | SMARCA2 (0.47) | ALDH1A1SMN1; SMN2IDO1CYP2C9CYP3A4 | |
| SCHEMBL20866546 | 0.68 | HTR1E (0.62) | ALDH1A1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL30846653 | 0.68 | NPC1 (0.55) | ALDH1A1SMN1; SMN2IDO1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116910-A1 | Heterocycles as WIP1 Inhibitors | PMV PHARMACEUTICALS, INC. | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116910-A1 | Heterocycles as WIP1 Inhibitors | WAPL, WHR1, G3BP1 | ALDH1A1 2418/4885SMN1; SMN2 3265/4885F2 4602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.