Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25713063 | 0.93 | LMNA (0.60) | LMNAP2RX7GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL1971598 | 0.89 | LMNA (0.52) | LMNAP2RX7GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL12856160 | 0.80 | LMNA (0.61) | LMNAP2RX7GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL30914523 | 0.79 | LMNA (0.59) | LMNAP2RX7GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL8640906 | 0.79 | LMNA (0.59) | LMNAP2RX7GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL21769866 | 0.78 | P2RX7 (0.59) | LMNAP2RX7GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL28280153 | 0.77 | LMNA (0.62) | LMNAP2RX7GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL25714094 | 0.77 | CYP1A2 (0.48) | LMNASMN1; SMN2ALDH1A1POLBMAPK1 | |
| SCHEMBL30848437 | 0.77 | P2RX7 (0.59) | P2RX7SMN1; SMN2MAPK1NPC1RAB9A | |
| SCHEMBL28281220 | 0.76 | LMNA (0.65) | LMNAP2RX7GAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | disclosed |