Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 8/20 | 0.59 |
| ▸ | HCN1 | O60741 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30848473 | 0.81 | MEN1 (0.64) | P2RX7HCN1HPGDMEN1KMT2A | |
| SCHEMBL13162647 | 0.80 | P2RX7 (0.58) | P2RX7HCN1HPGDSMN1; SMN2MAPK1 | |
| SCHEMBL13634515 | 0.80 | P2RX7 (0.58) | P2RX7HCN1HPGDSMN1; SMN2MAPK1 | |
| SCHEMBL13161950 | 0.79 | P2RX7 (0.57) | P2RX7HCN1HPGDSMN1; SMN2MAPK1 | |
| SCHEMBL13162929 | 0.79 | HCN1 (0.62) | P2RX7HCN1HPGD | |
| SCHEMBL13634448 | 0.78 | P2RX7 (0.56) | P2RX7HCN1HPGDSMN1; SMN2MAPK1 | |
| SCHEMBL13162890 | 0.78 | P2RX7 (0.56) | P2RX7HCN1HPGDSMN1; SMN2MAPK1 | |
| SCHEMBL13161956 | 0.78 | P2RX7 (0.56) | P2RX7HCN1HPGDSMN1; SMN2MAPK1 | |
| SCHEMBL30848670 | 0.77 | MEN1 (0.54) | P2RX7HCN1HPGDMEN1KMT2A | |
| SCHEMBL30848447 | 0.77 | LMNA (0.59) | P2RX7SMN1; SMN2MAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | disclosed |