Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30848679 | 0.80 | CNR2 (0.64) | HPGDNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL30014039 | 0.79 | CNR2 (0.63) | HPGDNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL30848463 | 0.79 | HPGD (0.60) | HPGDNPC1RAB9AP2RX7HTT | |
| SCHEMBL7446480 | 0.76 | P2RX7 (0.47) | HPGDNPC1RAB9ASMN1; SMN2P2RX7 | |
| SCHEMBL397839 | 0.75 | HPGD (0.51) | HPGDNPC1RAB9ASMN1; SMN2P2RX7 | |
| SCHEMBL30848469 | 0.73 | HPGD (0.46) | HPGDNPC1RAB9ASMN1; SMN2P2RX7 | |
| SCHEMBL31079661 | 0.73 | HPGD (0.46) | HPGDNPC1RAB9ASMN1; SMN2P2RX7 | |
| SCHEMBL23141447 | 0.71 | KCNA5 (0.45) | HPGDSMN1; SMN2L3MBTL1HTT | |
| SCHEMBL15129252 | 0.71 | HPGD (0.60) | HPGDNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL4914462 | 0.71 | HPGD (0.60) | HPGDNPC1RAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | disclosed |