Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MIF | P14174 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4862241 | 1.00 | MAOA (0.53) | MAOAMAOBCYP2A6CES1PDPK1 | |
| SCHEMBL910775 | 0.88 | CES1 (0.52) | MAOAMAOBCYP2A6CES1PDPK1 | |
| SCHEMBL2952083 | 0.76 | MAOA (0.44) | MAOAMAOBCYP2A6CES1PDPK1 | |
| SCHEMBL1451688 | 0.74 | MAOA (0.46) | MAOAMAOBCYP2A6CES1PDPK1 | |
| SCHEMBL11144928 | 0.72 | CES1 (0.73) | MAOAMAOBCYP2A6CES1PDPK1 | |
| SCHEMBL28867674 | 0.71 | MAOA (0.63) | MAOAMAOBCYP2A6CES1PDPK1 | |
| SCHEMBL568779 | 0.70 | TSHR (0.71) | MAOAMAOBCYP2A6CES1PDPK1 | |
| SCHEMBL31430380 | 0.70 | TSHR (0.71) | MAOAMAOBCYP2A6CES1PDPK1 | |
| SCHEMBL30505637 | 0.70 | CYP2A6 (0.68) | MAOAMAOBCYP2A6CES1PDPK1 | |
| SCHEMBL3103992 | 0.70 | CYP2A6 (0.68) | MAOAMAOBCYP2A6CES1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7794907-B2 | Hydrazone compound, electrophotographic photoreceptor comprising the hydrazone compound, and image forming apparatus equipped with the electrophotographic photoreceptor | SHARP KABUSHIKI KAISHA (JP) | 2010-09-14 | — | — | US | disclosed |
| CN-1325469-C | Hydrazone compound, electrophotographic photoreceptor comprising the hydrazone compound, and image forming apparatus equipped with the electrophotographic photoreceptor | SHARP KK (JP) | 2007-07-11 | — | — | CN | disclosed |
| US-20060057481-A1 | Hydrazone compound, electrophotographic photoreceptor comprising the hydrazone compound, and image forming apparatus equipped with the electrophotographic photoreceptor | SHARP KABUSHIKI KAISHA (JP) | 2006-03-16 | — | — | US | disclosed |
| CN-1746153-A | Hydrazone compound, electrophotographic photoreceptor comprising the hydrazone compound, and image forming apparatus equipped with the electrophotographic photoreceptor | SHARP KK (JP) | 2006-03-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060057481-A1 | Hydrazone compound, electrophotographic photoreceptor comprising the hydrazone compound, and image forming apparatus equipped with the electrophotographic photoreceptor | ALDH1A2, HCN1, HVCN1 | MAOA 3176/4885MAOB 3140/4885CYP2A6 2648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.