Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.58 |
| ▸ | PPIA | P62937 | 6/20 | 0.56 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 3/20 | 0.49 |
| ▸ | RXRB | P28702 | 2/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2426791 | 1.00 | LTA4H (0.58) | LTA4HMAPK14PPIASGMS2KDM4E | |
| Hydrochloric Acid SCHEMBL10705444 | 0.98 | LTA4H (0.57) | LTA4HMAPK14PPIASGMS2KDM4E | |
| SCHEMBL8883647 | 0.90 | ABCB1 (0.50) | LTA4HMAPK14PPIASGMS2KDM4E | |
| SCHEMBL8883987 | 0.89 | KMT2A (0.56) | LTA4HMAPK14PPIARXRARXRB | |
| SCHEMBL8881484 | 0.88 | HTR1A (0.56) | LTA4HMAPK14PPIASGMS2ALDH1A1 | |
| SCHEMBL8883136 | 0.88 | PPIA (0.55) | LTA4HMAPK14PPIASGMS2RXRA | |
| SCHEMBL8883654 | 0.88 | RXRA (0.50) | LTA4HMAPK14PPIAKDM4EALDH1A1 | |
| SCHEMBL13380651 | 0.87 | LTA4H (0.55) | LTA4HMAPK14PPIASGMS2ALDH1A1 | |
| SCHEMBL2840715 | 0.87 | LTA4H (0.59) | LTA4HMAPK14PPIASGMS2RXRA | |
| SCHEMBL29836285 | 0.87 | LTA4H (0.55) | LTA4HMAPK14PPIASGMS2RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120004901-A | As WRN helicase inhibitors triazolo cyclic compounds | 上海济煜医药科技有限公司 | 2025-05-16 | — | — | CN | disclosed |
| WO-2025049746-A1 | COMPOSITIONS COMPRISING WERNER SYNDROME HELICASE INHIBITORS AND METHODS OF USING THE SAME | EIKON THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |
| CN-118684684-A | Compounds as WRN helicase inhibitors | 上海济煜医药科技有限公司 | 2024-09-24 | — | — | CN | disclosed |
| WO-2024076155-A1 | NOVEL COMPOUND AS YEATS DOMAIN INHIBITOR | 노보렉스 주식회사 | 2024-04-11 | — | — | WO | disclosed |