Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KCNA3 | P22001 | 10/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.52 |
| ▸ | HCN4 | Q9Y3Q4 | 5/20 | 0.51 |
| ▸ | HCN1 | O60741 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30848473 | 0.91 | MEN1 (0.64) | MEN1ALDH1A1KMT2AKCNA3P2RX7 | |
| SCHEMBL30848437 | 0.77 | P2RX7 (0.59) | MEN1KMT2AP2RX7HCN1HPGD | |
| SCHEMBL28448824 | 0.77 | HPGD (0.50) | MEN1ALDH1A1KMT2AKCNA3P2RX7 | |
| SCHEMBL31275290 | 0.77 | MEN1 (0.37) | MEN1ALDH1A1KMT2AKCNA3P2RX7 | |
| SCHEMBL30848511 | 0.74 | MEN1 (0.60) | MEN1ALDH1A1KMT2AKCNA3P2RX7 | |
| SCHEMBL31275179 | 0.73 | MEN1 (0.48) | MEN1ALDH1A1KMT2AKCNA3P2RX7 | |
| SCHEMBL30848447 | 0.70 | LMNA (0.59) | ALDH1A1KCNA3P2RX7TP53 | |
| SCHEMBL3455503 | 0.70 | MEN1 (1.00) | MEN1ALDH1A1KMT2AKCNA3 | |
| SCHEMBL31685209 | 0.70 | KCNA3 (1.00) | MEN1ALDH1A1KMT2AKCNA3 | |
| SCHEMBL1946359 | 0.70 | KCNA3 (1.00) | MEN1ALDH1A1KMT2AKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | disclosed |