SCHEMBL30849682

SCHEMBL30849682

O[C@H](CCc1ccccc1Cl)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.53
SLC6A4 P31645 1/20 0.53
SLC6A3 Q01959 1/20 0.53
HTR1A P08908 1/20 0.48
TAAR1 Q96RJ0 3/20 0.47
RIPK1 Q13546 1/20 0.46
CASR P41180 1/20 0.44
CYP51A1 Q16850 1/20 0.44
LMNA P02545 1/20 0.44
HTR3E A5X5Y0 1/20 0.43
HTR3B O95264 1/20 0.43
HTR3A P46098 1/20 0.43
HTR3D Q70Z44 1/20 0.43
HTR3C Q8WXA8 1/20 0.43
KDM4E B2RXH2 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7809658 0.86 RIPK1 (0.53) HTR1ARIPK1LMNAKDM4EL3MBTL1
SCHEMBL30565246 0.82 SLC6A2 (0.62) SLC6A2SLC6A4SLC6A3TAAR1LMNA
SCHEMBL249172 0.82 SLC6A2 (0.62) SLC6A2SLC6A4SLC6A3TAAR1LMNA
SCHEMBL11050916 0.79 TAAR1 (0.48) TAAR1RIPK1LMNAKDM4EL3MBTL1
SCHEMBL31005083 0.79 TAAR1 (0.48) TAAR1RIPK1LMNAKDM4EL3MBTL1
SCHEMBL31005082 0.79 TAAR1 (0.48) TAAR1RIPK1LMNAKDM4EL3MBTL1
SCHEMBL936320 0.78 PPARG (0.58) SLC6A2SLC6A4SLC6A3RIPK1LMNA
SCHEMBL5835025 0.78 PPARG (0.54) SLC6A2SLC6A4SLC6A3RIPK1LMNA
SCHEMBL499868 0.78 PPARG (0.54) SLC6A2SLC6A4SLC6A3RIPK1LMNA
SCHEMBL477470 0.78 PPARG (0.54) SLC6A2SLC6A4SLC6A3RIPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117865776-A Method for directly converting aromatic alkyne into chiral alcohol by one-pot method 三峡大学 2024-04-12 CN disclosed