SCHEMBL30850163

SCHEMBL30850163

CC(=O)c1cc(C)cnc1NC(=O)OC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ATR Q13535 1/20 0.39
LCK P06239 3/20 0.38
NAMPT P43490 1/20 0.37
MAPKAPK2 P49137 2/20 0.35
GSK3B P49841 1/20 0.35
DYRK1A Q13627 1/20 0.35
SYK P43405 1/20 0.35
MAPK1 P28482 1/20 0.35
RORC P51449 2/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA9 Q16790 1/20 0.34
CYP17A1 P05093 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
MAP4K4 O95819 1/20 0.34
TRPA1 O75762 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15599330 0.84 SYK (0.42) ATRLCKMAPKAPK2GSK3BDYRK1A
SCHEMBL7416577 0.84 LCK (0.45) ATRLCKMAPKAPK2GSK3BDYRK1A
SCHEMBL30850162 0.81 ADRA2A (0.34) ATRLCKMAPKAPK2MAPK1RORC
SCHEMBL7091197 0.80 L3MBTL1 (0.40)
SCHEMBL30026311 0.75 NAMPT (0.46) ATRNAMPTMAPK1CYP17A1RXFP1
SCHEMBL8984337 0.75 NAMPT (0.46) ATRNAMPTMAPK1CYP17A1RXFP1
SCHEMBL16753674 0.74 GSK3B (0.45) ATRLCKNAMPTGSK3BDYRK1A
SCHEMBL3269413 0.73 ATR (0.41) ATRLCKNAMPTMAPKAPK2GSK3B
SCHEMBL24364156 0.72 MAPKAPK2 (0.40) ATRLCKMAPKAPK2SYKCA12
SCHEMBL3728331 0.72 RXFP1 (0.40) LCKMAPK1CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4605400-A1 NOVEL TRIHETEROCYCLIC COMPOUNDS Idience Co., Ltd. (KR) 2025-08-27 EP disclosed
WO-2024085661-A1 NOVEL TRIHETEROCYCLIC COMPOUNDS ILDONG PHARMACEUTICAL CO., LTD. (KR) 2024-04-25 WO disclosed